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SAS Institute Inc., Cary, NC. Results {#Sec8} ======= Subject characteristics {#Sec9} ----------------------- A total of 287 subjects were enrolled in the study, 218 (76%) were females, the mean age was 46.3 years old (SD = 8.6). The baseline characteristics of the study population are presented in Table [1](#Tab1){ref-type="table"}. The most common comorbidities were hypertension, followed by obesity. Most subjects had hypertension with no prior treatment, and only 5.9% of the subjects had previously been treated with antihypertensive medications. The mean estimated glomerular filtration rate (eGFR) was 83.5 mL/min/1.73 m^2^ (SD = 19.6).Table 1Baseline characteristics of study population.All patients\n(*N* = 287)Baseline characteristicsMedian (IQR) or n(%)Age, years46.3 (39.7-54.3)Age category, n(%)≤39 years of age78 (27.3)40-59 years of age203 (70.0)≥60 years of age18 (6.3)Sex, n(%)Male81 (28.0)Female206 (72.0)Race, n(%)Caucasian259 (89.7)Hispanic5 (1.7)Asian11 (3.9)Other5 (1.7)Body mass index, kg/m^2^29.8 (25.8-34.6)Systolic blood pressure, mmHg131 (125--140)Diastolic blood pressure, mmHg80 (70-90)Antihypertensive treatment, n(%)No212 (74.4)Yes75 (25.6)Metformin, n(%)Yes175 (60.1)No112 (39.0)Other antidiabetic medications, n(%)Yes53 (18.3)No234 (81.7)Prevalent disease category, n(%)Diabetes56 (19.6)CAD142 (49.0)CVD132 (46.1)Others^a^7 (2.4)eGFR, mL/min/1.73m^2^

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